Maeve Labs Buy · from $28 a pack
Essential™
The foundational mitochondria coffee
Buy · from $28 a pack
Benefits Mechanisms Evidence Compared
Benefits

What you’ll notice, and when.

Some of it the first morning. Some of it by week three. Some of it you never feel, and it matters most. Everything here comes from a human trial at or under the dose in your mug.

Focus Mental energy Mental clarity Fatigue Sleep
Recall Stress and mood Strength Endurance Heart Glucose
Blood pressure Immunity Joints Mood Memory under stress
In order of arrival
Signal
Build
Fuel
Protect
Clear
The first hour
Focus arrives.

Coffee with L-theanine, the amino acid in green tea that takes the edge off caffeine: sharper attention and less distraction from the first cup30.

In the mug
Coffee, L-theanine, rhodiola
In Rewire too
The first morning
Energy, on two fuels at once.

Your brain burns glucose and ketones side by side. The mug carries both: 5 grams of sugar, and MCT oil your liver turns into ketones40. Creatine, at 9 g (5 g in Rewire), fuels the brain as well as the body41. No crash at hour four.

In the mug
Sugar, MCT oil, creatine
In Rewire too
The first morning
Brain fog lifts.

Brain fog: the thought is there and you cannot quite reach it. It lifts with the first mug. Caffeine with L-theanine sharpens attention and reaction30, while MCT's ketones open the brain's second energy channel, bringing clarity and quieting the noise40. What keeps it lifted builds over weeks: creatine at 9 g (5 g in Rewire) raises brain phosphocreatine, the reserve that thinking draws from, over eight weeks41.

In the mug
Coffee, L-theanine, MCT oil, creatine
In Rewire too
Weeks two to four
The deeper fatigue lifts.

Rhodiola acts within two weeks51, creatine within the first week41. Underneath, NAD+ — the coenzyme every cell uses to make energy, and which falls with age — doubles in the blood by day fourteen2, while creatine keeps building in the brain3.

"Way more fatigued without it. Those couple weeks I was drinking your coffee daily, I felt amazing."

— Pilot customer, two weeks on, one week off

This works while you take it39.

In the mug
Creatine, NMN
In Rewire too
Month three
Recall sharpens.

The last to arrive: twelve weeks is how long the brain takes to replace nine-tenths of its mitochondria33, with lion’s mane supplying the NGF to build them well. A protocol, not a pick-me-up.

In the mug
Lion’s mane, PQQ, creatine
In Rewire too
Every day, unfelt
The cycle, running.

Below sensation, not below measurement. By day your cells signal for new mitochondria, build them, fuel them, and protect them; by night they clear the worn ones out. Clearing fades most with age, and spermidine raises it32. One morning mug carries all five stages.

Apigenin slows CD38, the enzyme that uses up most of the body’s NAD+46. Taken every morning, it builds over three weeks47.

In the mug
Lion’s mane, NMN, creatine, ergothioneine, spermidine, apigenin
Along the way

What else it does.

Each one at or under the amount in the mug. The marker on each card is where it lands on the timeline above.

Weeks two to four
Stress and mood

Lower anxiety, better mood, and better sleep after a month21.

In the mug
L-theanine, rhodiola
In Rewire too
Weeks two to four
Mood

Reishi eases anxiety and lifts mood and vitality over a month59.

In the mug
Reishi
Week six
A lower heart-risk marker

Six weeks of betaine lowers high homocysteine, the amino acid that tracks heart risk, by 12%23.

In the mug
Betaine
Week six
Memory under stress

Six weeks of phosphatidylserine brings a chronically stressed cortisol response back to normal55 and improves recall60.

In the mug
Phosphatidylserine
Weeks ten to twelve
Healthy glucose metabolism

Ten weeks of NMN improves how the body handles glucose37. Twelve weeks of creatine lowers HbA1c, the three-month blood-sugar marker38.

In the mug
NMN, creatine
In Rewire too
Month three
Memory

Memory improves over twelve weeks of PQQ26, and recall that had begun to slip comes back over sixteen weeks of lion’s mane39. A year of erinacine A improves cognition and daily function1.

In the mug
Lion’s mane, PQQ, creatine
In Rewire too
Month three
Mental fatigue

Twelve weeks of ubiquinol, the active form of CoQ10: everyday fatigue eases, less tired and less sleepy after a long mental task27.

In the mug
Ubiquinol
Month three
Joints

Knee pain after exercise eases by week twelve on collagen peptides58.

In the mug
Collagen peptides
Weeks six to eight
Blood pressure

Six to eight weeks of pterostilbene lowers systolic blood pressure by 7.8 mmHg35.

In the mug
Pterostilbene
Throughout
Immunity

Reishi β-glucan raises T-cell and natural-killer counts56. Eight weeks of cordyceps raises first-line immune activity when it runs low54.

In the mug
Reishi, cordyceps
Throughout
Strength

Creatine builds strength and lean mass, the most replicated finding in sports nutrition34.

In the mug
Creatine
In Rewire too
Weeks two to twelve
Endurance

Cordyceps raises the point where lactate starts to build, over twelve weeks66, and after three weeks you last longer at full effort67. Creatine refills the reserve between hard efforts, so you can repeat them34. Taurine raises exercise time and distance within two weeks50. Luteolin raises the oxygen your muscles pull from the blood52. NMN raises how far you can walk over two months28. Reishi raises VO₂max and work capacity over a month59. MCT raises the fat you burn64.

In the mug
Cordyceps, creatine, taurine, luteolin, NMN, reishi, MCT
In Rewire too
Rate your week. Take $7 off your first pack.
Focus, mental energy, mental clarity, fatigue, endurance, and sleep — six questions, about a minute. After that, $1 toward every pack for each day you rate, up to $7 a pack. Your own progress chart.
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